Sensorion, le début d’une belle aventure

PRECLINICAL GROUP LEADER F/M – CELL MODEL PLATFORM

Montpellier - CDI

Entreprise

Sensorion is a pioneering clinical-stage biotech company, which specializes in the development of novel therapies to restore, treat and prevent hearing loss disorders, a significant global unmet medical need. 

Sensorion has built a unique R&D technology platform to expand its understanding of the pathophysiology and etiology of inner ear related diseases, enabling it to select the best targets and modalities for drug candidates. Its portfolio combines both small molecule programs and a preclinical portfolio of inner ear gene therapies. 

Its clinical-stage portfolio includes one Phase 2 product: SENS-401 (Arazasetron) progressing in a planned Phase 2 Proof of Concept clinical study of SENS-401 in Cisplatin-Induced Ototoxicity (CIO) and, with partner Cochlear Limited, a study of SENS-401 in patients scheduled for cochlear implantation.

Sensorion has entered into a broad strategic collaboration with Institut Pasteur focused on the genetics of hearing. It has two gene therapy programs aimed at correcting hereditary monogenic forms of deafness including deafness caused by a mutation of the gene encoding for Otoferlin, and hearing loss related to mutation in GJB2 gene to potentially address important hearing loss segments in adults and children. The Company is also working on the identification of biomarkers to improve diagnosis of these underserved illnesses. 

www.sensorion-pharma.com

Poste

Mission

 

Based in Montpellier, the Preclinical Group Leader of the Cell Model platform F/M proposes, develops and coordinates R&D projects carried out by the team in the context of the company’s strategic plans.   

She/He is recognized as an internal expert in her/his field. She/He works in proactive collaboration with all the other team leaders in the department.   

She/He works in accordance with ethical rules, current regulations, good laboratory practices (GLP) and health and safety rules.   

Reporting to the Preclinical Director, Preclinical Group Leader of the Cell Model platform F/M is called upon to work in collaboration with other teams in the company on various projects, or even to lead cross-functional technical projects. 

 

Main Activities

 

Platform 

 

  • Proposal and management of R&D projects for her/his team: development and implementation of in vitro cellular models including in particular those allowing the study of the biology, physiopathology, etiology and therapies of ear diseases internal, but also the target identification and validation, drug screening, the characterization of the activity and the in vitro pharmacology of molecules for therapeutic purposes; 
  • Contribution to project development plans, supervision of writing and validation of project deliverables for her/his team; 
  • Realization of certain experimental manipulations due to its scientific expertise in order to support projects, develop new methods or train the team; 
  • Propose and implement the scientific development and technical innovation strategy of the platforms for which she/he is responsible; 
  • Supervision of subcontracting related to its studies and projects (specifications, implementation of contracts, monitoring, etc.); 
  • Organization, realization and restitution of a technical, scientific and clinical monitoring activity on the areas of expertise covered by her/his team; 
  • Exchange of high-level and cross-disciplinary scientific and technical information, acts as a cross-disciplinary expert with other teams and with top management; 
  • Obtaining and structuring innovative data with a view to obtaining patents; participates in interactions with service provider patent firms; 
  • Realization of external communications on the R&D projects of her/his team or on the company; Representation of the company abroad. 

  

Team Management 

 

  • Planning and organization of the daily R&D activities of her/his team; 
  • Supervision of reports and publications on the R&D projects of her/his team; 
  • Management of the human resources of her/his team (recruitment, evaluation, training, etc.) in conjunction with top management; 
  • Management of the allocation of means/resources (human, financial, deadlines, materials…) according to the results and the strategy in connection with top management; 
  • Ensure the scientific and technical development of the members of her/his team; 
  • Guarantor of the application of procedures and regulations for the platforms under her/his responsibility; 
  • Guarantor of the quality and integrity of the results of scientific analysis and their reporting. 

 

______________________________________________________________________

STAY ALERT !

 

Several incidents involving organizations and individuals claiming to be fraudulently recruiting on behalf of Sensorion have recently been identified.

The objective of the fraudsters is to extort money from applicants by requesting additional expenses (medical devices, travel agency, visa fees, etc.) or obtaining personal data (bank details, address, etc.). Please note that Sensorion, its subsidiaries or the recruitment firms they appoint during the hiring process do not request financial contributions or bank details from candidates under any circumstances.

We take this situation very seriously and are taking all possible actions to identify and put an end to this type of fraud.

 

We recommend the following good practices:

 

  • do not make any payment for any reason;
  • do not respond to unsolicited job offers or job offers of which you think the origin is suspicious;
  • apply only via the contact form below;

 

Never communicate personal or financial information to strangers.

 

 

Profil

  • PhD or equivalent; 
  • Ideally, at least 7 years of experience in a similar position or great scientific expertise attested by numerous publications in the field of biology, physiopathology, etiology and therapies of inner ear diseases and associated cell models, cell biology, screening and evaluation of the activity of drug candidates in vitro, with experience in personnel management; 
  • The position requires a good knowledge of current techniques for studying cell regeneration, stem cell and iPSC biology, organoids culture; 
  • The position requires a good knowledge of current techniques of biochemistry, molecular biology, cell biology, development of assays and in vitro screening tests, immunolabeling, cell imaging and proteomics; 
  • Knowledge of GxP, main ICH and Quality Assurance;  
  • Significant experience in a health industry: biotech, pharmaceutical industry, health industry provider, etc. would be a plus; 
  • Experience in the field of rare diseases, hearing and/or gene therapy would be a plus; 
  • Fluent French & English. 

Postuler

Postuler